Why NSAID Use is a Bad Idea

| July 9, 2017 | 0 Comments

NSAIDs are a class of drugs available with or without a prescription. Common ones include: Celebrex, Meloxicam, Aleve and the generic ibuprofen. The acronym stands for “Non-Steroidal Anti-inflammatory Drugs”. The designation being applied as these drugs sub-planted prednisone and other steroid drugs in the treatment of joint pain.

NSAIDs, like most prescription drugs, work because they poison your body by interrupting normal function. Steroids inhibit your immune system. NSAIDs block the formation of some critical proteins (cytokines) that are involved in producing pain and fever during inflammation. Inflammation is a normal part of your body’s healing process. It’s happens for a good reason.

When you introduce these poisons into your, system it’s like feces in the swimming pool, the effects cover the entire pool. (Try getting that visual out of your head😝). NSAIDs, and other drugs, effect every cell in your body.

“Heart attacks” and strokes are not the only deadly effects of NSAIDs like ibuprofen and Aleve. They also cause bleeding ulcers and kidney failure. Many professional athletes like Alonzo Mourning and Sean Elliot have nearly died due to NSAID exposure.

In general, prescription drug use is similar to drinking sea water while stranded at sea or cannibalizing your friends during a Donner Party event (Wikipedia for you youngsters). It’s something you do as a last resort that normal people would never do. If an intelligent person develops thirst, they drink regular water. That addresses the root cause of the problem. Drinking sea water long-term makes your problem worse, as does long-term prescription drug use.

How do you get off NSAIDs? Most NSAID use is for joint pain relief. I started taking them for knee pain after skiing. However, once I realized the pain was due to worn down cartilage in my knees, I started doing things to rebuild the cartilage (glucosamine, chondroitin, pentosan, MSM). Autoimmune conditions like rheumatoid arthritis are another major reason people poison their heart, livers, kidneys, and stomachs with NSAIDs. These conditions are caused by critter overgrowth. Address the root cause of the problem. People with low back pain are also big NSAID consumers.

Consequences from NSAIDs appear suddenly. The “heart attack”, stroke, kidney failure, or stomach bleeding seem to happen all of a sudden. I spent many hours in the ER pumping blood from the stomachs of NSAID users. Work with a doctor who will help you deal with the root cause of your pain. Even short term use for fever is not a good idea.

 

FDA Strengthens NSAID Warning for Heart, Stroke Risks

 

The US Food and Drug Administration (FDA) has strengthened an existing label warning that nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the risk for heart attack or stroke, according to an agency alert sent today.

Following a comprehensive review of new safety information, the FDA is requiring the drug labels of all prescription and over-the-counter (OTC) NSAIDs to be updated to reflect the increased risk. Prescription and OTC nonaspirin NSAIDs already include information about the risk for heart attack and stroke with NSAIDs, either of which can lead to death, the FDA states in a news release.

Prescription nonaspirin NSAID labels first included “Boxed Warning” and “Warnings and Precaution” sections in 2005. Since that time, the FDA reviewed new safety information on prescription and OTC NSAIDs that included observational studies, a large combined analysis of clinical trials, and other scientific publications.

The FDA’s Arthritis Advisory Committee and Drug Safety and Risk Management Advisory Committee discussed these studies at a joint meeting on February 10-11, 2014.

The updated labels for prescription NSAIDS will include the following information:

  • Heart attack or stroke risk can increase as early as the first weeks of NSAID use, and the risk may increase with longer NSAID use. The risk appears to be greater at higher doses.
  • Although the risk was previously thought to be similar for all NSAIDs, more recent information calls this into question. The FDA now says that there is insufficient information to determine whether the risk is higher or lower for one NSAID compared with another.
  • A large number of studies show that patients with or without heart disease or risk factors for heart disease are at increased risk for heart attack or stroke. Study estimates of the extent of increased risk are varied, depending on the medications and doses studied.
  • In general, the risk for heart attack or stroke after NSAID use is greater in patients with heart disease or risk factors for it because their risk is higher at baseline.
  • Patients who take NSAIDs after a first heart attack were more likely to die in the year after the heart attack compared with those who did not take NSAIDs after their first heart attack.
  • Patients are at increased risk for heart failure with NSAID use.

The FDA recommends that patients and healthcare professionals remain alert for cardiac adverse effects for the duration of NSAID use. Those taking NSAIDs should seek immediate medical attention if they have symptoms including chest pain, shortness of breath or difficulty breathing, weakness in one part or side of their body, or slurred speech.

More information on today’s alert is available on the FDA website.

(This article was originally posted on Medscape.com.  Note: free member sign-up may be required to fully access articles on this site.)

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Category: General Health, Heart Health, Inflammation, Joint Health, Pain Management

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