Prenatal Counseling – Best Health Before Conception

| June 11, 2017 | 0 Comments

Thyroid hormone is important to normal human embryonic development in general, but it’s especially critical to normal development of cells with high energy requirements. This includes the brain, heart and gut.

As we age past 27, thyroid levels gradually fall. This is compounded in pregnancy by a rise in the level of the estrogen, estradiol. This causes a functional reduction in thyroid activity, as estradiol increases the production of thyroid binding globulin. This protein binds to thyroid hormone, making it as dysfunctional as a bicycle with a padlock.

The fetus does not begin to make thyroid hormone until the third trimester so is totally dependent on maternal levels until then. If hypothyroidism is not recognized and addressed during the first trimester, irreversible cellular structural anatomy in the brain is caused. The range of insult can be from lowered I.Q. to cretinism. The next test after a positive pregnancy test should be a TSH.

The father’s contribution to autism may come from what are called single nucleotide polymorphisms (SNPs). DNA must be replicated with each new cell, including sperm cells. Think of taking an original document and making a copy. You then take that copy and make another copy. Repeating this process produces progressively lower quality copies. This is why the new skin you produce at 70 is different from the new skin produced at 18. Old sperm likely has SNPs. Can this be reversed? My physical exam yesterday and research on telomeres says “Yes”.

This introduces a new era of prenatal counseling where couples must be encouraged, at any age, to get in their best health before conception.

The article below is reprinted from, “Autism risk higher in kids of teen moms, couples with large age gaps” by ANI, June 10, 2015.

Autism risk higher in kids of teen moms, couples with large age gaps

The largest-ever multinational study of parental age and autism risk has found increased autism rates among the children of teen moms and among children whose parents have relatively large gaps between their ages.

The study also confirmed that older parents are at higher risk of having children with autism. The analysis included more than 5.7 million children in five countries.

Co-author Michael Rosanoff said that by linking national health registries across five countries, they created the world’s largest data set for research into autism’s risk factors. The size allowed them to look at the relationship between parents’ age and autism at a much higher resolution.

Co-author Sven Sandin added that although parental age is a risk factor for autism, it is important to remember that, overall, the majority of children born to older or younger parents will develop normally.

The study found that Autism rates were 66 percent higher among children born to dads over 50 years of age than among those born to dads in their 20s. Autism rates were 28 percent higher when dads were in their 40s versus 20s.

Autism rates were 15 percent higher in children born to mothers in their 40s, compared to those born to moms in their 20s and were 18 percent higher among children born to teen moms than among those born to moms in their 20s.

Autism rates rose still higher when both parents were older, in line with what one would expect if each parent’s age contributed to risk. Autism rates also rose with widening gaps between two parents’ ages. These rates were highest when dads were between 35 and 44 and their partners were 10 or more years younger. Conversely, rates were high when moms were in their 30s and their partners were 10 or more years younger.

The study appears in the Journal of Molecular Psychiatry.

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Category: General Health, Hormone Support, Research, Women's Health

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