Q & A – Protecting Against Newborn Infections

| September 17, 2017 | 0 Comments

Q: Hey Dr. Mitchell,

We’ve met a few times many years ago. I’m curious as a medical student now and as a father how best to protect my newborn daughter from a number of conditions I’ve personally seen in the hospital that have significant sequelae and mortality. What’s the best way to protect against pneumococcal and meningococcal infections in a newborn besides breast feeding? Also, regarding MMR, I assume heard immunity is enough. I’m against vaccines, but seeing the effects of the diseases first hand in patient wards I’m concerned as many of these patients were immigrants with no vaccine history. Any thoughts?

Dr Fitt: Important to first understand how the immune system works. Glaring deficiency in medical school curriculum. Give a listen first to Bonnie Basseler’s TED talk on bacteria on YouTube. Important to understand that most of our DNA is microbial, not human. Immune system has two basic moieties, humoral and cellular. Humoral is underwritten by the production of cytokines, complement, and antibodies. Antibodies are “smart bombs” that target specific critters. Complement and cytokines are indiscriminate and therefore can also cause the collateral damage we see with most western medical conditions.

Macrophages are critical to optimal immune system function. Once they engulf a critter, they digest it using hydrochloric acid and lysozymes (This digestion of critters and antigen production also occurs when hydrochloric acid is produced by parietal cells with each meal). This creates antigens. These antigens are then regurgitated back to the cell membranes to the major histocompatibility complex. From there, they are presented to B cells to stimulate antibody production. Antibodies attach to critters and initiate the immune cascade of cytokine production and summoning killer T cells. When the system is optimally functional, we get critter exposure, antibody production and immunity from a broad spectrum of critters. This is why it’s important to let your kid get dirty, expose them to animals, especially farm animals and let them eat boogers.

One class of critters in the microbiome is Candida. Candida albicans predominates, but there is also Candida glabrata, the evil twin. You’ve seen both if you’ve done a critical care rotation. They flourish when there is immune compromise. Candida always exists as sessile, single celled symbionts in the colon. They metabolize waste and free up nutrients for us to absorb. However, if environmental conditions facilitate overgrowth, the single cells coalesce into hyphae and become mobile.

Candida produce chemicals called gliotoxins. Gliotoxins poison macrophages. This compromises the ability to routinely destroy critters and make antigens/antibodies. Soooo, keeping Candida levels under control is critical to being bulletproof against internal and external critters. Candida overgrowth opens the door for other fungi, bacteria and viruses.

Three primary ways we keep Candida under control–temperature, HCl production, and glycemic control. The combustion of glucose in mitochondria in the presence of oxygen and triiodothyronine creates energy. Same energy equation an internal combustion engine–fuel +oxygen +spark. A byproduct of that energy is the 98.6-degree temperature that is optimal for keeping Candida at bay. If thyroid levels are suboptimal, body temp declines and Candida levels rise. Thyroid levels are often suboptimal in neonates, especially if maternal age was 27 or above. That is the age thyroid levels start a natural decline. As women, have decided to put off pregnancy until later years, we have more children born with compromised thyroid production. This is why we see such an epidemic rise in asthma, autism, food “allergies”, skin conditions, etc. Function may mature with age and the child will “grow out of” some conditions. Sometimes thyroid hormone must be supplemented.

Parietal cells in the gastric lumen produce enough HCl to make the pH of the stomach three million times that of arterial pH (You should look this up in Guyton’s Textbook of Human Physiology). This is accomplished by hydrogen ion pumps. Hydrogen ion pumps require energy. So, you can see thyroid function impacts your ability to produce HCl in the gastric lumen and also in macrophages. This domino effect subtracts one of your most powerful defense against critter overgrowth, HCl production. If HCl production is low, it must be supplemented with a betaine HCl supplement. Google “Symptoms of hydrochloric acid deficiency” to become familiar with clinical signs/symptoms. In adults, an MCV is an indirect indicator as red blood cells (RBC’s) get bigger as B 12 levels decline. B 12 levels decline as HCl production declines. An MCV above 85 is red flag for inadequate HCl production. HCl production determines who gets poliomyelitis and who doesn’t, who gets food poisoning and who doesn’t. Inadequate HCl production was the springboard for the evolution of the vaccine industry. That’s why two cohorts, the young and the elderly, are targeted. Both are low thyroid/low hydrochloric acid.

Glycemic control is manipulated by what we eat. One of the fundamentals of the BALi Eating Plan is choosing foods with a glycemic index of 55 or below. Higher blood sugar levels facilitate Candida overgrowth. The other fundamental of BALi is choosing foods that have naturally occurring critter killers like proanthocyanidins, isothiocyanates, resveratrol, phenolic compounds, terpenoids, cannabinoids, etc.

Soooo, in addition to providing antibodies via breast feeding, make sure thyroid and HCl production is optimal. Follow BALi Eating Plan. Mom should be taking supplemental iodine/iodide as these halogens attach to cell membrane’s omega 3 fats (from black seed oil) to provide critter protection similar to chlorine in swimming pools, bromine in baked goods and fluorine in dentifrices. She should also keep vitamin D levels 70-100. Supplements usually best for this also. Cholecalciferol is actually a steroidal (cholesterol base) hormone like testosterone, progesterone, DHEA and estrogens. One of the things it causes DNA to transcribe is cathelicidins. These antimicrobial peptides also help us keep critter levels in check.

Follow this protocol and there is no need for man-made vaccines.

Tags: , , , , , , ,

Category: Children's Health, Frequently Asked Questions, General Health

Leave a Reply

Your email address will not be published. Required fields are marked *